3 The second angel poured his bowl into the sea, and it became like the blood of a dead man, and every living thing died that was in the sea. 4 The third angel poured his bowl into the rivers and the fountains of water, and they became blood. 5 And I heard the angel of water say, "Just art thou in these thy judgments, thou who art and wast, O Holy One. 6 For men have shed the blood of saints and prophets, and thou hast given them blood to drink. It is their due!"
Matthew Henry's Commentary on Revelation 16:3-6
Commentary on Revelation 16:1-7
(Read Revelation 16:1-7)
We are to pray that the will of God may be done on earth as it is done in heaven. Here is a succession of terrible judgments of Providence; and there seems to be an allusion to several of the plagues of Egypt. The sins were alike, and so were the punishments. The vials refer to the seven trumpets, which represented the rise of antichrist; and the fall of the enemies of the church shall bear some resemblance to their rise. All things throughout their earth, their air, their sea, their rivers, their cities, all are condemned to ruin, all accursed for the wickedness of that people. No wonder that angels, who witness or execute the Divine vengeance on the obstinate haters of God, of Christ, and of holiness, praise his justice and truth; and adore his awful judgments, when he brings upon cruel persecutors the tortures they made his saints and prophets suffer.