3 The second angel poured his bowl into the sea, and it became like the blood of a corpse, and every living thing in the sea died. 4 The third angel poured his bowl into the rivers and the springs of water, and they became blood. 5 And I heard the angel of the waters say, "You are just, O Holy One, who are and were, for you have judged these things; 6 because they shed the blood of saints and prophets, you have given them blood to drink. It is what they deserve!"
Matthew Henry's Commentary on Revelation 16:3-6
Commentary on Revelation 16:1-7
(Read Revelation 16:1-7)
We are to pray that the will of God may be done on earth as it is done in heaven. Here is a succession of terrible judgments of Providence; and there seems to be an allusion to several of the plagues of Egypt. The sins were alike, and so were the punishments. The vials refer to the seven trumpets, which represented the rise of antichrist; and the fall of the enemies of the church shall bear some resemblance to their rise. All things throughout their earth, their air, their sea, their rivers, their cities, all are condemned to ruin, all accursed for the wickedness of that people. No wonder that angels, who witness or execute the Divine vengeance on the obstinate haters of God, of Christ, and of holiness, praise his justice and truth; and adore his awful judgments, when he brings upon cruel persecutors the tortures they made his saints and prophets suffer.