16 At my first defence no man stood with me, but all deserted me. May it not be imputed to them. 17 But the Lord stood with [me], and gave me power, that through me the proclamation might be fully made, and all [those of] the nations should hear; and I was delivered out of the lion's mouth.

Matthew Henry's Commentary on 2 Timothy 4:16-17

Commentary on 2 Timothy 4:14-18

(Read 2 Timothy 4:14-18)

There is as much danger from false brethren, as from open enemies. It is dangerous having to do with those who would be enemies to such a man as Paul. The Christians at Rome were forward to meet him, Acts 28, but when there seemed to be a danger of suffering with him, then all forsook him. God might justly be angry with them, but he prays God to forgive them. The apostle was delivered out of the mouth of the lion, that is, of Nero, or some of his judges. If the Lord stands by us, he will strengthen us in difficulties and dangers, and his presence will more than supply every one's absence.