16 At my first defence no one took my part, but all forsook me: may it not be laid to their account. 17 But the Lord stood by me, and strengthened me; that through me the message might me fully proclaimed, and that all the Gentiles might hear: and I was delivered out of the mouth of the lion.

Matthew Henry's Commentary on 2 Timothy 4:16-17

Commentary on 2 Timothy 4:14-18

(Read 2 Timothy 4:14-18)

There is as much danger from false brethren, as from open enemies. It is dangerous having to do with those who would be enemies to such a man as Paul. The Christians at Rome were forward to meet him, Acts 28, but when there seemed to be a danger of suffering with him, then all forsook him. God might justly be angry with them, but he prays God to forgive them. The apostle was delivered out of the mouth of the lion, that is, of Nero, or some of his judges. If the Lord stands by us, he will strengthen us in difficulties and dangers, and his presence will more than supply every one's absence.