21 And Isaiah son of Amoz sendeth unto Hezekiah, saying, 'Thus said Jehovah, God of Israel, That which thou hast prayed unto me concerning Sennacherib king of Asshur— 22 this 'is' the word that Jehovah spake concerning him: Trampled on thee, laughed at thee, Hath the virgin daughter of Zion, Behind thee shaken the head hath the daughter of Jerusalem.
Matthew Henry's Commentary on Isaiah 37:21-22
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Isaiah 37 is the same as 2 Kings 19. Thus, please see the commentary on 2 Kings 19.