16 But when he was strong, his heart was lifted up, so that he did corruptly, and he trespassed against Yahweh his God; for he went into the temple of Yahweh to burn incense on the altar of incense. 17 Azariah the priest went in after him, and with him eighty priests of Yahweh, who were valiant men: 18 and they withstood Uzziah the king, and said to him, It pertains not to you, Uzziah, to burn incense to Yahweh, but to the priests the sons of Aaron, who are consecrated to burn incense: go out of the sanctuary; for you have trespassed; neither shall it be for your honor from Yahweh God. 19 Then Uzziah was angry; and he had a censer in his hand to burn incense; and while he was angry with the priests, the leprosy broke forth in his forehead before the priests in the house of Yahweh, beside the altar of incense. 20 Azariah the chief priest, and all the priests, looked on him, and behold, he was leprous in his forehead, and they thrust him out quickly from there; yes, himself hurried also to go out, because Yahweh had struck him. 21 Uzziah the king was a leper to the day of his death, and lived in a separate house, being a leper; for he was cut off from the house of Yahweh: and Jotham his son was over the king’s house, judging the people of the land.
Matthew Henry's Commentary on 2 Chronicles 26:16-21
Commentary on 2 Chronicles 26:16-23
(Read 2 Chronicles 26:16-23)
The transgression of the kings before Uzziah was, forsaking the temple of the Lord, and burning incense upon idolatrous altars. But his transgression was, going into the holy place, and attempting to burn incense upon the altar of God. See how hard it is to avoid one extreme, and not run into another. Pride of heart was at the bottom of his sin; a lust that ruins many. Instead of lifting up the name God in gratitude to him who had done so much for him, his heart was lifted up to his hurt. Men's pretending to forbidden knowledge, and seeking things too high for them, are owing to pride of heart. The incense of our prayers must be, by faith, put into the hands of our Lord Jesus, the great High Priest of our profession, else we cannot expect it to be accepted by God, Revelation 8:3. Though Uzziah strove with the priests, he would not strive with his Maker. But he was punished for his transgression; he continued a leper to his death, shut out from society. The punishment answered the sin as face to face in a glass. Pride was at the bottom of his transgression, and thus God humbled him, and put dishonour upon him. Those that covet forbidden honours, forfeit allowed ones. Adam, by catching at the tree of knowledge which he might not eat of, debarred himself of the tree of life which he might have eaten of. Let all that read say, The Lord is righteous. And when the Lord sees good to throw prosperous and useful men aside, as broken vessels, if he raises up others to fill their places, they may rejoice to renounce all worldly concerns, and employ their remaining days in preparation for death.