21 While they were eating, he said, "I tell you the truth, one of you will betray me." 22 Greatly distressed, each one asked in turn, "Am I the one, Lord?" 23 He replied, "One of you who has just eaten from this bowl with me will betray me. 24 For the Son of Man must die, as the Scriptures declared long ago. But how terrible it will be for the one who betrays him. It would be far better for that man if he had never been born!" 25 Judas, the one who would betray him, also asked, "Rabbi, am I the one?" And Jesus told him, "You have said it."
Matthew Henry's Commentary on Matthew 26:21-25
Commentary on Matthew 26:17-25
(Read Matthew 26:17-25)
Observe, the place for their eating the passover was pointed out by Christ to the disciples. He knows those hidden ones who favour his cause, and will graciously visit all who are willing to receive him. The disciples did as Jesus had appointed. Those who would have Christ's presence in the gospel passover, must do what he says. It well becomes the disciples of Christ always to be jealous over themselves, especially in trying times. We know not how strongly we may be tempted, nor how far God may leave us to ourselves, therefore we have reason not to be high-minded, but to fear. Heart-searching examination and fervent prayer are especially proper before the Lord's supper, that, as Christ our Passover is now sacrificed for us, we may keep this feast, renewing our repentance, our faith in his blood, and surrendering ourselves to his service.