19 "But I wanted to know more. I was curious about the fourth animal, the one so different from the others, the hideous monster with the iron teeth and the bronze claws, gulping down what it ripped to pieces and trampling the leftovers into the dirt. 20 And I wanted to know about the ten horns on its head and the other horn that sprouted up while three of the original horns were removed. This new horn had eyes and a big mouth and spoke arrogantly, dominating the other horns. 21 I watched as this horn was making war on God's holy people and getting the best of them. 22 But then The Old One intervened and decided things in favor of the people of the High God. In the end, God's holy people took over the kingdom. 23 "The bystander continued, telling me this: 'The fourth animal is a fourth kingdom that will appear on earth. It will be different from the first three kingdoms, a monster kingdom that will chew up everyone in sight and spit them out. 24 The ten horns are ten kings, one after another, that will come from this kingdom. But then another king will arrive. He will be different from the earlier kings. He will begin by toppling three kings. 25 Then he will blaspheme the High God, persecute the followers of the High God, and try to get rid of sacred worship and moral practice. God's holy people will be persecuted by him for a time, two times, half a time.
Matthew Henry's Commentary on Daniel 7:19-25
Commentary on Daniel 7:15-28
(Read Daniel 7:15-28)
It is desirable to obtain the right and full sense of what we see and hear from God; and those that would know, must ask by faithful and fervent prayer. The angel told Daniel plainly. He especially desired to know respecting the little horn, which made war with the saints, and prevailed against them. Here is foretold the rage of papal Rome against true Christians. St. John, in his visions and prophecies, which point in the first place at Rome, has plain reference to these visions. Daniel had a joyful prospect of the prevalence of God's kingdom among men. This refers to the second coming of our blessed Lord, when the saints shall triumph in the complete fall of Satan's kingdom. The saints of the Most High shall possess the kingdom for ever. Far be it from us to infer from hence, that dominion is founded on grace. It promises that the gospel kingdom shall be set up; a kingdom of light, holiness, and love; a kingdom of grace, the privileges and comforts of which shall be the earnest and first-fruits of the kingdom of glory. But the full accomplishment will be in the everlasting happiness of the saints, the kingdom that cannot be moved. The gathering together the whole family of God will be a blessedness of Christ's coming.