12 And the sixth let what was in his vessel come out on the great river Euphrates; and it became dry, so that the way might be made ready for the kings from the east. 13 And I saw coming out of the mouth of the dragon, and out of the mouth of the beast, and out of the mouth of the false prophet, three unclean spirits, like frogs. 14 For they are evil spirits, working signs; who go out even to the kings of all the earth, to get them together to the war of the great day of God, the Ruler of all. 15 (See, I come as a thief. Happy is he who is watching and keeps his robes, so that he may not go unclothed, and his shame be seen.) 16 And they got them together into the place which is named in Hebrew Armageddon.
Matthew Henry's Commentary on Revelation 16:12-16
Commentary on Revelation 16:12-16
(Read Revelation 16:12-16)
This probably shows the destruction of the Turkish power, and of idolatry, and that a way will be made for the return of the Jews. Or, take it for Rome, as mystical Babylon, the name of Babylon being put for Rome, which was meant, but was not then to be directly named. When Rome is destroyed, her river and merchandise must suffer with her. And perhaps a way will be opened for the eastern nations to come into the church of Christ. The great dragon will collect all his forces, to make one desperate struggle before all be lost. God warns of this great trial, to engage his people to prepare for it. These will be times of great temptation; therefore Christ, by his apostle, calls on his professed servants to expect his sudden coming, and to watch that they might not be put to shame, as apostates or hypocrites. However Christians differ, as to their views of the times and seasons of events yet to be brought to pass, on this one point all are agreed, Jesus Christ, the Lord of glory, will suddenly come again to judge the world. To those living near to Christ, it is an object of joyful hope and expectation, and delay is not desired by them.