Man of sin: a designation of Antichrist given in 2 Thessalonians 2:3-10, usually regarded as descriptive of the Papal power; but "in whomsoever these distinctive features are found, whoever wields temporal and spiritual power in any degree similar to that in which the man of sin is here described as wielding it, he, be he pope or potentate, is beyond all doubt a distinct type of Antichrist."